l-proline catalyzed synthesis of betti bases and biscoumarin derivatives
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abstract
the direct three component modified mannich reaction via condensation of aldehydes, 2-naphthol or 2,7-naphthalendiol and piperidine to generate betti bases has been carried out over l-proline (20 mol%) with high efficiency under solvent free conditions at 70 oc. also, the reaction of aromatic aldehyde and 4-hydroxycoumarin in the presence of l-proline (20 mol%) in the ethanol under reflux conditions, lead to biscoumarin derivatives
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Journal title:
iranian journal of catalysisPublisher: islamic azad university, shahreza branch
ISSN 2252-0236
volume 5
issue 2 2015
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